Guidelines for the treatment of malaria
Recommen- dations on the use of Sulfadoxine - Pyrimethamine (SP) for Intermittent Preventive Treatment during Pregnancy (IPT) in areas of moderate to high resistance to SP in the African Region
Changing Malaria Treatment Policy to Artemisinin-Based Combinations
ACTs
Photo by Bonnie Gillespie, Johns Hopkins University
Since October 14th 2008, the AS/AQ co-formulated fixed dose combination from Sanofi-Aventis, in partnership with DNDi, is prequalified by the WHO. See the WHO prequalification page for details.
The following ACTs are currently recommended by WHO for the treatment of uncomplicated falciparum malaria (alphabetical order):
- artemether-lumefantrine,
- artesunate + amodiaquine,
- artesunate + mefloquine,
- artesunate + sulfadoxine–pyrimethamine.
Links & resources:
- Compilation of past and planned procurement of Artemisininbased Combination Therapies (ACTs) from available public sources
- ACTWatch includes Malaria drug database online
- Request for Expression of Interest (EOI) from ACTs manufacturers
- Prequalification Programme
- Prequalified Antimalarial Drugs
Suppliers whose artemisinin-based combination antimalarial medicines have been found acceptable, in principle, for procurement by UN agencies - Antimalarial Medicines (currently available for procurement by WHO)
- WHO malaria treatment policies
- CNAP Artemisia Research Project updates
- Active Pharmaceutical Ingredient Requirements for the manufacture of ACTs
Position paper of the RBM Procurement and Supply Management Working Group
Responsibly improving access to ACTs in the private sector
Report of the MoH (Uganda)-MMV Workshop Series
- Guidance document on pharmacovigilance for countries participating in AMFm Phase 1
- Including Pharmacovigilance in Global Fund's Round 8 Proposal [en français]
- Budgeting and Timeline for Establishing Pharmacovigilance Capacity
- Steps for Completing Global Fund's Round 8 Proposal for Requesting funds for Pharmacovigilance
- Steps for Accessing Funding from Global Fund for Pharmacovigilance for Ongoing grants: Midway or during start of Phase 2
Global Fund Grants for Malaria
Summary of Lessons Learned in the Implementation of ACT Policies in:
Ghana,
Nigeria,
Guinea-Bissau,
Summary