16.01.2012

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Announcements / Press Releases

RBM Launches Search for New Executive Director [RBM] — (English)
Application Deadline: 31 January 2012 ...

Counterfeit and substandard antimalaria drugs threaten crisis in Africa, experts warn [Wellcome Trust Press Release] — (English)
In the video below, Paul Newton, Head of the Laos arm of the Trust's Major Overseas Programmes in South-east Asia, discusses his research in the region and shows examples of counterfeit packaging...

Boston College researchers locate protein that could 'turn off' deadly disease carrier [Boston College via LabSpaces] — (English)
Researchers from Boston College have discovered a protein that plays a pivotal role in the progression of the deadly diseases toxoplasmosis and malaria and shown that its function could be genetically blocked in order to halt the progress of the parasite-borne illnesses, the team reports in the current edition of the journal Science...

ThinkMarketing Discusses Edinburgh Scientists Making A Malaria Breakthrough [Free-Press-Release.com] — (English)
Scientists from The University of Edinburgh created a vaccine for Malaria, which has now been further developed after a study revealed a fundamental protein in the blood of African children, who were naturally exposed to the infected mosquitoes that cause the disease. A source from ThinkMarketing has commented on this, saying...

Vector Control Working Group (VCWG) updates [RBM VCWG] — (English)
Documents of the recent Work Stream meetings posted on the RBM web site...

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Articles requiring subscription

Rolling Malaria Indicator Surveys (rMIS): A Potential District-Level Malaria Monitoring and Evaluation (M&E) Tool for Program Managers [Am J Trop Med Hyg 2012 vol. 86 no. 1 96-98 doi: 10.4269/ajtmh.2012.11-0397] — (English)
The potential applicability of this promising M&am;E approach for district-level program managers and control efforts is discussed...

Malaria Survey in Post-Earthquake Haiti—2010 [Am J Trop Med Hyg 2012 vol. 86 no. 1 29-3110.4269/ajtmh.2012.11-0431 ] — (English)
Malaria RDTs were useful in the post-disaster setting where logistical and technical constraints limited the use of microscopy...

Review: Malaria Chemoprophylaxis for Travelers to Latin America [Am J Trop Med Hyg 2011 vol. 85 no. 6 1015-1024 doi: 10.4269/ajtmh.2011.11-0464 ] — (English)
Primaquine should be strongly considered for nonpregnant, G6PD-nondeficient patients traveling to vivax-endemic areas of Latin America, and it has the added benefit of being the only drug to protect against malaria relapses...

Hospital-Based Prevalence of Malaria and Dengue in Febrile Patients in Bangladesh [Am J Trop Med Hyg 2012 vol. 86 no. 1 58-64 10.4269/ajtmh.2012.11-0190 ] — (English)
We conducted a nationwide study at six tertiary hospitals from December 2008 through November 2009 to investigate etiologies of febrile illnesses in Bangladesh...

The Increase of Imported Malaria Acquired in Haiti among US Travelers in 2010 [Am J Trop Med Hyg 2012 vol. 86 no. 1 9-10 doi: 10.4269/ajtmh.2012.11-0394 ] — (English)
Non-adherence to malaria chemoprophylaxis remains a nearly universal modifiable risk factor among these cases...

Prevalence of Malaria among Patients Attending Public Health Facilities in Maputo City, Mozambique [Am J Trop Med Hyg 2011 vol. 85 no. 6 1002-1007 doi: 10.4269/ajtmh.2011.11-0365 ] — (English)
We conducted a health facility-based survey to estimate the prevalence of malaria among febrile patients at health facilities (HFs) in Maputo City...

Performance of a Histidine-Rich Protein 2 Rapid Diagnostic Test, Paracheck Pf®, for Detection of Malaria Infections in Ugandan Pregnant Women [Am J Trop Med Hyg 2012 86:93-95; doi:10.4269/ajtmh.2012.10-0631] — (English)
Field-based sensitive tests for malaria in pregnancy are urgently needed...

Occupational Activities Associated with a Reported History of Malaria among Women Working in Small-Scale Agriculture in South Africa [Am J Trop Med Hyg 2011 85:805-810; doi:10.4269/ajtmh.2011.11-0092] — (English)
This study suggests that certain agricultural activities and types of crop production may increase the risk for malaria among women working in small-scale agriculture...

Randomized, Prospective, Three-Arm Study to Confirm the Auditory Safety and Efficacy of Artemether-Lumefantrine in Colombian Patients with Uncomplicated Plasmodium falciparum Malaria [Am J Trop Med Hyg 2012 86:75-83; doi:10.4269/ajtmh.2012.11-0192] — (English)
The results support the continued safe and efficacious use of artemether-lumefantrine in uncomplicated falciparum malaria...

Vaccine Reduces Malaria in African Children [AJN, American Journal of Nursing: January 2012 - Volume 112 - Issue 1 - p 69 doi: 10.1097/01.NAJ.0000410368.04427.7c] — (English)
The RTS,S/AS01 vaccine reduced the risk of clinical and severe malaria by half in young African children...

Host defense against malaria favors Salmonella [Nature Medicine, 18, 21–22 (2012) doi:10.1038/nm.2636] — (English)
The beneficial cytoprotective effects of heme oxygenase-1 (HO-1) in malaria infection are counterpoised by higher susceptibility to nontyphoidal Salmonella (NTS) bacteremia. A new study in mice co-infected with malaria and Salmonella provides a mechanism for the long-recognized association between malaria and NTS infection in African children...

Evaluation of the antiplasmodial and cytotoxicity potentials of husk fiber extracts from Cocos nucifera, a medicinal plant used in Nigeria to treat human malaria [Hum Exp Toxicol. 2012 Jan 12] — (English)
The isolation of the active compounds from coco mestiço husks has not yet been done...

IL-12Rβ2 Is Essential for the Development of Experimental Cerebral Malaria [The Journal of Immunology January 11, 2012 1101978 ] — (English)
We document a novel link between IL-12Rβ2 and lymphotoxin-α, TNF-α, and IFN-γ expression, key cytokines for ECM pathogenesis...

Mild Plasmodium falciparum malaria following an episode of severe malaria is associated with induction of the interferon pathway in Malawian children [Infect Immun. doi: 10.1128/​IAI.06008-11 IAI.06008-11] — (English)
Malaria is a leading cause of morbidity and mortality in children worldwide...

Larvicidal and ovicidal properties of leaf and seed extracts of Delonix elata (L.) Gamble (Family: Fabaceae) against malaria (Anopheles stephensi Liston) and dengue (Aedes aegypti Linn.) (Diptera: Culicidae) vector mosquitoes [Parasitology Research DOI: 10.1007/s00436-011-2802-9] — (English)
This is the first report on the mosquito larvicidal and ovicidal activities of the reported D. elata plant...

Geographic differentiation of polymorphism in the Plasmodium falciparum malaria vaccine candidate gene SERA5 [Vaccine] — (English)
The present study points to the importance of investigating whether biased geographical distribution for SNPs and repeat variants in the OR and SR regions affect the reactivity of human serum antibodies to variants...

A cost-effectiveness analysis of provider interventions to improve health worker practice in providing treatment for uncomplicated malaria in Cameroon: a study protocol for a cluster randomized controlled trial [Trials 2012, 13:4 doi:10.1186/1745-6215-13-4] — (English)
Cost-effectiveness will be presented in terms of the primary outcome and a range of secondary outcomes, including changes in provider knowledge. Costs will be estimated from a societal and provider perspective using standard economic evaluation methodologies...